Endocrine Abstracts

Aim of the research: To study diabetes insipidus (DI) prevalence in the Republic of Uzbekistan (RUZ) according to National Register.Materials and methods: Computerized database has developed which covers all 12 regions of RUZ and Republic of Karakalpakstan. Database includes 1822 patients with diabetes insipidus.Results: According to the register there are 1822 patients with DI which occurs in men and women with similar rate –...

The purpose of the study: Is to study the frequency of thyroid diseases in adolescents (boys and girls) in 2 regions of the Republic of Uzbekistan.Material and methods.: We have been examined and surveyed in the framework of screening just for the period from January 1, 2021 to April 1, 2021 - 1023 boys and girls in the two regions of RUZ - 523 adolescents were examined in the Djizakh region and 500 adolescents in the Namangan region Aged from 11 to 15 y...

The aim: To study the functional state of axis of hypophysis-gonads for women with PCOS.Material and methods of investigation: Under our supervision in the department of neuroendocrinology of The Center of Endocrinology of PHM of Republic of Uzbekistan ambulatory in a period from September 2015 for July, 2016 120 patients of fertile age were inspected with polycystic ovary syndrome (PCOS). Middle age of patients – 25.5±4.3 years. The remoteness...

Aim: To study features of family inheritance in patients of non-functional pituitary adenomas (NFPA) in Uzbekistan.Materials and methods: We included 71 patients with NFPA, intrasellar localization (mean size >3 mm). Mean age was from 18 to 70 years old (range 44.5±3.85 years). Of 71 patients, 30 (42.3%) were men and 41 (57.7%) were women.All patients underwent clinical and biochemical evaluations including endocrine check...

Aim of the research: To study relationship between GH levels and acromegaly complications development in different therapy approaches.Patients and methods: We evaluated 50 patients with GH secreting adenomas referred to CCSSE from 1999 to 2004. Age of patients was from 19 to 63 years-old (mean age 40±19 years-old). Duration of the disease was from 1 to 23 years.Methods: Clinical and biochemical tests of neurological status; RI...

Aim of the research: To study clinical and epidemiologic features of acromegaly in the Republic of Uzbekistan.Patients and methods: We observed acromegalic patients registered from 2007 to 2009 who are dispensarized in the regions of the country. Of the 369 patients 143 were males (38.7%) and 226 females (61.3%). Mean age of the patients was 42.6 years-old. Duration of the disease varied from 1 to 31 years.Results: According to the...

Aim of the research: To study the rate of vascular complications in acromegaly in the Republic of Uzbekistan.Patients and methods: We observed acromegalic patients registered from 2007 to 2009 who are dispensarized in the regions of the country. Of the 369 patients 143 were males (38.7%) and 226 females (61.3%). Mean age of the patients was 42.6 years-old. Duration of the disease varied from 1 to 31 years.Results: We assessed the r...

Aim of the research: To study long and short-term therapy effectiveness with dopamine agonists in acromegaly.Patients and methods: Three hundred and sixty-nine patients with acromegaly registered by December, 1 2009 in the Republic of Uzbekistan. Of these patients we observed 20 cases with GH-secreting pituitary adenoma. Age of the patients was from 19 to 63 years-old (mean age 40±19 years-old), duration of the disease was from 1 to 23 years. Patien...

Aim: The aim of investigation to determine clinical aggressiveness diagnostic markers in patients with non-functional pituitary adenomas (NFPA), and growth hormone deficiency (GHD) in the formation of gravity neuroendocrine disease symptoms.Material and methods: We observed in 87 patients (including man – 44 women – 43) of which have a verified diagnosis of NFPA after surgery – 31 which were subjected transnasal adenomectomy of the pituiat...